9 research outputs found
Derivar casos de uso de un glosario
- Publication venue
- Publication date
- 01/10/2012
- Field of study
Get PDFEl modelado del negocio permite detectar debilidades en los procesos del negocio dando pie a proyectar mejoras eficientes involucrando sistemas de software. Utilizando modelos en lenguaje natural se achica la brecha de comunicación entre los usuarios y los ingenieros de software, y cuando además se trata de modelos como los casos de uso o los escenarios, éstos estimulan la imaginación para proyectar mejoras en los procesos del negocio con sistemas de software, tanto por parte de los ingenieros de software como de los propios usuarios. Se presenta en este artículo un enfoque para el modelado del negocio construyendo casos de uso a partir de un glosario específico, denominado léxico extendido del lenguaje. Este enfoque aborda una modalidad middle-out para el modelado de los casos de uso, ofreciendo ventajas de arranque frente a otras propuestas.Business modeling helps detecting weaknesses in business processes enabling the envisagement of efficient improvements involving software systems. The use of natural language-based models reduces the communication gap between users and software engineers, and when those models are scenarios or use cases, they stimulate the imagination of software engineers and users to project improvements in business processes applying software systems. We show in the article an approach to business modeling building use cases derived form an specific glossary called language extended lexicon. This approach encourages a middle-out fashion while modeling use cases and gives a bootstrap advantage against other proposals.Workshop de Ingeniería de Software y Bases de Datos (WISBD)Red de Universidades con Carreras en Informática (RedUNCI
Derivar casos de uso de un glosario
- Publication venue
- Publication date
- 01/10/2008
- Field of study
Get PDFEl modelado del negocio permite detectar debilidades en los procesos del negocio dando pie a proyectar mejoras eficientes involucrando sistemas de software. Utilizando modelos en lenguaje natural se achica la brecha de comunicación entre los usuarios y los ingenieros de software, y cuando además se trata de modelos como los casos de uso o los escenarios, éstos estimulan la imaginación para proyectar mejoras en los procesos del negocio con sistemas de software, tanto por parte de los ingenieros de software como de los propios usuarios. Se presenta en este artículo un enfoque para el modelado del negocio construyendo casos de uso a partir de un glosario específico, denominado léxico extendido del lenguaje. Este enfoque aborda una modalidad middle-out para el modelado de los casos de uso, ofreciendo ventajas de arranque frente a otras propuestas.Business modeling helps detecting weaknesses in business processes enabling the envisagement of efficient improvements involving software systems. The use of natural language-based models reduces the communication gap between users and software engineers, and when those models are scenarios or use cases, they stimulate the imagination of software engineers and users to project improvements in business processes applying software systems. We show in the article an approach to business modeling building use cases derived form an specific glossary called language extended lexicon. This approach encourages a middle-out fashion while modeling use cases and gives a bootstrap advantage against other proposals.Workshop de Ingeniería de Software y Bases de Datos (WISBD)Red de Universidades con Carreras en Informática (RedUNCI
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
- Author
- 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Get PDFThis study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Spectral signatures of L-DOPA-induced dyskinesia depend on L-DOPA dose and are suppressed by ketamine
- Author
- Albin
- Alcacer
- Alonso-Frech
- Andersson
- Andrade
- Bartlett
- Bartlett
- Belić
- Belluscio
- Berke
- Brown
- Brunel
- Buzsáki
- Buzsáki
- Caixeta
- Calabresi
- Calon
- Canolty
- Carlén
- Carta
- Cenci
- Chase
- Cho
- Cohen
- Colgin
- Cools
- Cools
- Cordon
- Cotzias
- Dalton
- Dekundy
- Del Bello
- DeLong
- delPino
- Devergnas
- Diamond
- Dupre
- Fieblinger
- Fries
- Galuske
- Gerhard
- Goetz
- Grieco
- Hakami
- Halje
- Hanganu
- Homayoun
- Hudson
- Hunt
- Hunt
- Johnson
- Kaufman
- Kirli
- Korotkova
- Kulikova
- Li
- Lim
- Lisman
- Lisman
- Litvak
- Lopez-Azcarate
- Lundblad
- Manduca
- Mavridis
- McNally
- Muthukumaraswamy
- Nestler
- Nicolás
- Niesters
- Oertel
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- Olanow
- Olszewski
- Perez
- Phoumthipphavong
- Picconi
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- Richter
- Rivolta
- Rothwell
- Rubenstein
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- Sherman
- Slaughter
- Sohal
- Swann
- Tamte
- Torta
- Towers
- Voytek
- Whittington
- Williams
- Yang
- Ye
- Yizhar
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- 'Elsevier BV'
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No full textPhotosynthetic characterization of flavodoxin-expressing tobacco plants reveals a high light acclimation-like phenotype
- Author
- Anabella F. Lodeyro
- Andriankaja
- Bailey
- Baker
- Ballottari
- Ballottari
- Belgio
- Belgio
- Blanco
- Brestic
- Ceccoli
- Coba de la Peña
- Czarnocka
- Dall'Osto
- Dinç
- Fan
- Grieco
- Guiamet
- Gururani
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- Hajirezaei
- Huang
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- Iovieno
- Janiak
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- Johnson
- Kaiser
- Kalaji
- Kalaji
- Klughammer
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- Lichtenthaler
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- Malkin
- Mathur
- Mayta
- Michael Melzer
- Mishanin
- Mohammad-Reza Hajirezaei
- Murashige
- Nicolás Figueroa
- Noctor
- Néstor Carrillo
- Pierella Karlusich
- Pierella Karlusich
- Pierella Karlusich
- Rochaix
- Rodrigo Gómez
- Rossi
- Sato
- Schansker
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- Stirbet
- Stirbet
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- Takagi
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- Townsend
- Tóth
- Tóth
- Urban
- Van Dingenen
- Wientjes
- Wood
- Yamori
- Zivcak
- Zivcak
- Zivcak
- Zurbriggen
- Zurbriggen
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- 'Elsevier BV'
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No full textSynthetic Strategies for Macrocyclic Peptides
- Author
- Akaji
- Albericio
- Albericio
- Albericio
- Alcaro
- Alcaro
- Ali
- Alsina
- Alsina
- Alsina
- Amore
- Anderson
- Andreu
- Andrews
- Arai
- Athanassopoulos
- Backes
- Barany
- Barlos
- Barlos
- Benoiton
- Bianco
- Bieraugel
- Biron
- Blackburn
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- Boas
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- Clark
- Cudic
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- Dahiya
- Dahiya
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- Darlak
- Davies
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- Dawson
- De Leon Rodriguez
- Delforge
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- Driggers
- Dumy
- Ehrlich
- El Haddadi
- El-Faham
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- Estep
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- Tam
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- Torres-García
- Torres-García
- Tromelin
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- Tulla-Puche
- Tulla-Puche
- Tyndall
- Valero
- Valeur
- Verdie
- Vig
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- Xiao-Yan
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- Yokoyama
- Yongye
- Yoo
- Yudin
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- Zhang
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- Zheng
- Zheng
- Zhu
- Publication venue
- 'Wiley'
- Publication date
- 18/08/2017
- Field of study
No full textPeptide macrocycles form an outstanding class of natural and synthetic bioactive compounds. This chapter discusses synthetic strategies for the final ring‐closing reaction by the widely employed and versatile processes of lactamization, lactonization, and disulfide bridge formation. According to the nature of the chemical bond found in the backbone, cyclic peptides can be classified in two major categories: homodetic peptides and heterodetic peptides. In principle, all methods suitable for peptide bond formation can be applied for head‐to‐tail macrocyclization of linear peptides; however the reaction usually proceeds more slowly than the corresponding bimolecular version. During synthesis design, the C‐terminal amino acid of the linear precursor and the coupling reagent should be carefully chosen to minimize epimerization at the C‐terminal residue during cyclization. In many cases, the solution‐phase strategy is the best choice for performing the macrocyclization step, especially when larger quantities of cyclic peptide are required
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Ćoza I
- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
Get PDFAimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Delaying surgery for patients with a previous SARS-CoV-2 infection
- Author
- A A Ali Karar
- A A Kerawala
- A A Marra
- A Abad Gurumeta
- A Abad-Motos
- A Abdelmajeed
- A Abdelrahman
- A Abdelsamed
- A Abdulkareem
- A Aboelkassem Ibrahim
- A Abouassi
- A Abreu da Silva
- A Abubakar
- A Acher
- A Aderombi
- A Adeyeye
- A Adiamah
- A Aggarwal
- A Aghayeva
- A Agnes
- A Agrawal
- A Ahmeidat
- A Aimé
- A Ajlan
- A Al-Habib
- A Al-Mohammad
- A Al-Mukhtar
- A Aladeojebi
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- V Vujanac
- V Yip
- V Zamvar
- V Šćepanović
- Veeru Kasivisvanathan
- W Butt
- W Campbell
- W Cymes
- W Garrett
- W H Khan
- W J Wong
- W Knight
- W Lee
- W Marx
- W McCormick
- W McGahan
- W Mugla
- W Oosterlinck
- W Raby-Smith
- W Smolka
- W Van Houdt
- W Yang
- Willemijn van der Plas
- Wong Mpk
- X De Sousa
- X Morales
- X S Tan
- Y Aawsaj
- Y Al-Tamimi
- Y Arkha
- Y Ayasra
- Y Bashir
- Y El Bouazizi
- Y Fayed
- Y H Lam
- Y Kanemitsu
- Y Kara
- Y Kirmizi
- Y Levy-Zauberman
- Y Litvina
- Y Perez
- Y T Liew
- Y Tanase
- Y Viswanath
- Y Ying
- Z Al-Ishaq
- Z Aldayri
- Z Aliyeva
- Z Bayhan
- Z Chia
- Z Dzamic
- Z H Belkhadir
- Z Inic
- Z Jawad
- Z Jezdic
- Z Katusic
- Z Krivokapic
- Z Lakkis
- Z Li
- Z M Barrett-Brown
- Z Mahasin
- Z Seymour
- Z Vilendecic
- Z Zakaria
- Á De la Hoz Rodríguez
- Á Fernández Camuñas
- É Ryan
- Ž Grubač
- А Камалов
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
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